3,259 research outputs found

    Mosquito Survey of Camp Gruber Training Center and Comparison with Other Oklahoma Military Bases

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    Army National Guard training requires personnel to occasionally visit wild areas for one weekend a month and two weeks a year. During these times, the soldiers may be exposed to mosquitoes and be at risk of mosquito-borne pathogens. Our survey investigated mosquitoes inhabiting Camp Gruber Military Training Base, and in the adjacent town of Braggs, OK. Thirty traps (10 BG Sentinel Traps and 20 modified CDC light traps) using CO2 as attractant were emplaced every other weekend for 48 hours (Friday morning and-Sunday morning) for 23 collection periods between mid-April and late October 2018. A total of 10,405 mosquitoes from 7 genera and 26 species were collected, representing about 40% of the 64 species known from Oklahoma. The majority (98.4%) of mosquitoes were collected from CDC traps, which mainly collected Culex spp. (71.8% of total). Of the BG trap-collected mosquitoes, 40.2% were Aedes spp. The most abundant species Culex, of which some can transmit West Nile Virus. A single adult Aedes aegypti was captured on the base in August, and was genetically similar to a single larva captured in May. Compared with other military bases in Oklahoma, Camp Gruber had the only Ae. aegypti, and the most Ae. vexans, Cx. erraticus, and An. quadrimaculatus among bases. Tinker Air Force Base and Fort Sill Army Base had the most Ae. albopictus collected. The capture of Ae. aegypti along with other important disease vector species highlights the need for regular season-long monitoring to protect troops during training. Information generated from this study was used to provide mosquito warnings for troops training on base, and as well as a mosquito management plan for Camp Gruber

    What Drives Users to Pay for Freemium Services? Examining People’s Willingness to Pay for Music Services

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    Freemium is intended to be a promising method that allows content providers to earn money now that Web 2.0 users feel entitled to free software. However, industries that use freemium, like the music industry, still struggle to cover their costs. Despite its practical relevance, no studies have investigated why customers are willing to pay for a service that can also be used for free. Based on the Theory of Planned Behavior, we developed a research model to identify antecedents of consumers’ intentions and attitudes towards the premium version of music services when a free version is available. The results of our survey with 157 participants show that using the free version has a negative impact on users’ intention to pay for the premium version. Our practical implications indicate that music service providers should focus on the premium product and introduce a time-limited freemium

    Music as a Service as an Alternative to Music Piracy? - An Empirical Investigation of the Intention to Use Music Streaming Services

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    Despite increasing acceptance of digital channels, total sales in the music business decreased by 31 % from 2004 to 2010. Music piracy is still considered one of the main causes for this. However, several studies found no effects or even positive effects of illegal downloading on record sales. In the past, piracy has been counteracted especially by prosecution and legal offers. Music as a Service (MaaS) represents a new, differing distribution approach in digital music. In contrast to the wellknown music platforms for so-called àla- carte downloads, such as the iTunes Store, MaaS possesses two important characteristics: transmission (streaming instead of downloading) and pricing model (flat rate instead of pay-perdownload). Therefore, the consumption of music by means of purchasing and downloading is replaced by a monthly payment service (paid MaaS) and an ad-supported (free MaaS) service. First user surveys suggest that many music pirates are making use of these offers. To find out if MaaS is an attractive distribution channel for music pirates, we developed a model to explain the intention to use MaaS based on the Theory of Planned Behavior. To empirically test this model, we surveyed 132 music pirates. Among others, the outcome shows that the intention to use free MaaS is mainly affected by the attitude towardsMaaS, while using paid MaaS is predominantly a result of the influence of users’ closest peers. The attitude towards MaaS is positively influenced by the desire to receive music recommendations, the payment type (in the form of a flat rate model), and the relative advantage of MaaS compared to illegal choices

    Seeing Through the Noise: Seismic Reflection Profiling in Urban Areas

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    Studies for urban hazard or resource assessment often take place in densely populated areas characterized by considerable cultural noise. These site conditions can severely compromise seismic reflection data quality. We have collected vibroseis and hammer (weight drop) seismic reflection data in a range of geologic conditions to image stratigraphy and structures in the upper one km along regional highways, city streets,and power line access roads. In addition to the challenges of safety and outreach, acquisition efforts along busy streets and highways often encounter poor receiver coupling and large-amplitude coherent noise from traffic and power lines. Although higher quality seismic reflection data may be obtained by simply choosing alternate sites with less cultural noise, modifications to the acquisition and processing step scan minimize the effects of cultural noise and poor coupling where profiling is most relevant. Flagging crews, flyers and public announcements assist with outreach and safety concerns, and the local news media are often enthusiastic about publicizing geologic studies. Recording long-record vibroseis data reduces the effects of noise by itself,but data quality can be further optimized by recording uncorrelated,unstacked data and applying precorrelation amplitude adjustments and filters. Recording individual hammer shots likewise allows gains or mutes to normalize or remove traffic noise prior to vertical stacking. Large numbers of receiver channels allow attenuation of random noise and velocity filtering to remove coherent noise. Because ground roll and normal moveout (NMO) corrections minimize near-surface coverage, asymmetric source-receiver geometry allows for additional near-surface fold while muting large amplitude ground rolland NMO stretch. Source and geophone coupling on road shoulder scan degrade signal quality due to variable materials and topography,but these problems are often addressed with static corrections. Our experience is that high-quality seismic data can be obtained in noisy urban areas, but many recorded channels and a careful attention to acquisition and processing procedures can significantly improve the results

    Thermally-driven morphing with high temperature composites

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    The thermal expansion mismatch between heat-resisting metals and high-temperature composite materials is explored as a method of achieving thermally-driven morphing in elevated-temperature environments, with an eye towards applications in variable-geometry hot structures in gas turbine engines. Three concepts are presented and demonstrated. The first thermal morphing system is a bimorph laminate which exploits the CTE mismatch between a titanium metal matrix composite and its parent titanium matrix material. The second concept is similar to the first, but uses a diffusion-bonded austenitic stainless steel alloy as the high expansion layer. The third concept utilizes a carbon fiber, silicon carbide matrix ceramic matrix composite joined to a stainless steel skin in a trailing-edge flap arrangement. Furnace-based experiments of cantilever-mounted specimens are performed to evaluate the displacement response of the metal-matrix and ceramic-matrix concepts at temperatures up to 606°C and 1035°C, respectively.</p

    Long Timescale fMRI Neuronal Adaptation Effects in Human Amblyopic Cortex

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    An investigation of long timescale (5 minutes) fMRI neuronal adaptation effects, based on retinotopic mapping and spatial frequency stimuli, is presented in this paper. A hierarchical linear model was developed to quantify the adaptation effects in the visual cortex. The analysis of data involved studying the retinotopic mapping and spatial frequency adaptation effects in the amblyopic cortex. Our results suggest that, firstly, there are many cortical regions, including V1, where neuronal adaptation effects are reduced in the cortex in response to amblyopic eye stimulation. Secondly, our results show the regional contribution is different, and it seems to start from V1 and spread to the extracortex regions. Thirdly, our results show that there is greater adaptation to broadband retinotopic mapping as opposed to narrowband spatial frequency stimulation of the amblyopic eye, and we find significant correlation between fMRI response and the magnitude of the adaptation effect, suggesting that the reduced adaptation may be a consequence of the reduced response to different stimuli reported for amblyopic eyes

    Characteristics and survival of patients with advanced cancer and p53 mutations.

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    P53 mutations are associated with invasive tumors in mouse models. We assessed the p53mutations and survival in patients with advanced cancer treated in the Phase I Program. Of 691 tested patients, 273 (39.5%) had p53 mutations. Patients with p53 mutations were older (p&lt;.0001) and had higher numbers of liver metastases (p=.005). P53 mutations were associated with higher numbers of other aberrations; PTEN (p=.0005) and HER2 (p=.003)aberrations were more common in the p53 mutation group. No survival difference was observed between patients with p53 mutations and those with wild-type p53. In patients with wild-type p53 and other aberrations, patients treated with matched-therapy against the additional aberrations had longer survival compared to those treated with non-matched-therapy or those who received no therapy (median survival, 26.0 vs. 11.8 vs. 9.8 months, respectively; p= .0007). Results were confirmed in a multivariate analysis (p= .0002). In the p53 mutation group with additional aberrations, those who received matched-therapy against the additional aberrations had survival similar to those treated with non-matched-therapy or those who received no therapy (p=.15). In conclusion, our results demonstrated resistance to matched-targeted therapy to the other aberrations in patients with p53 mutations and emphasize the need to overcome this resistance
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